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Mitsuhiro ASAKUMA

Osaka Medical College
Osaka, Japan
MD
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Optical coherence tomography (OCT) of the colon and its mesentery (including virtual sentinel node biopsy) by natural orifice transluminal endoscopic surgery
Optical coherence tomography (OCT) is capable of 2–3mm slicing in opaque samples and so provides real-time cross-sectional images from the specimen. OCT can also achieve resolutions approaching that of conventional histology (c. 2–5μm) as it employs very short wave near-infrared light with precise interferometric detection. Although now mainly used in ophthalmology, OCT has already been found to have clinical applications in dermatology, cardiology, neurology, gynecology and gastroenterology. Dr. Ronan Cahill have deployed a commercially available probe (NIRIS™, Imulax Corporation, Cleveland OH, USA) via the working channel of a gastroscope used as a N.O.T.E.S. peritoneoscope in an experimental model. By this means, high-resolution real-time images mesenteric sentinel nodes have been obtained. Placing such a probe on the surface of the node should provide examination of the tissue to a depth of 2mm. In this video, we show the application of this technique in an experimental model.
R Cahill, M Asakuma, J Trunzo, SJ Schomisch, J Leroy, B Dallemagne, J Marescaux, J Marks
Surgical intervention
9 years ago
181 views
2 likes
0 comments
07:42
Optical coherence tomography (OCT) of the colon and its mesentery (including virtual sentinel node biopsy) by natural orifice transluminal endoscopic surgery
Optical coherence tomography (OCT) is capable of 2–3mm slicing in opaque samples and so provides real-time cross-sectional images from the specimen. OCT can also achieve resolutions approaching that of conventional histology (c. 2–5μm) as it employs very short wave near-infrared light with precise interferometric detection. Although now mainly used in ophthalmology, OCT has already been found to have clinical applications in dermatology, cardiology, neurology, gynecology and gastroenterology. Dr. Ronan Cahill have deployed a commercially available probe (NIRIS™, Imulax Corporation, Cleveland OH, USA) via the working channel of a gastroscope used as a N.O.T.E.S. peritoneoscope in an experimental model. By this means, high-resolution real-time images mesenteric sentinel nodes have been obtained. Placing such a probe on the surface of the node should provide examination of the tissue to a depth of 2mm. In this video, we show the application of this technique in an experimental model.
Gastric lymphatic mapping for sentinel node biopsy by natural orifice transluminal endoscopic surgery (NOTES)
This video demonstrates fully how NOTES can facilitate 'cherry-picking' of sentinel nodes from the perigastric lymph basins (including the retropyloric space) after gastroscopic lymphatic mapping of a site in the stomach in an experimental model. It is proposed that this could be partnered with advanced endoscopic resective techniques such as Submucosal Endoscopic Dissection (SED) in order to allow definitive endoscopic excision of early stage gastric cancers.
This video is reproduced here by kind permission of Surgical Endoscopy.
2008 Sep 24. [Epub ahead of print]. PMID: 18813997 [PubMed - as supplied by publisher]

R Cahill, M Asakuma, S Perretta, B Dallemagne, J Marescaux
Surgical intervention
9 years ago
220 views
3 likes
0 comments
07:16
Gastric lymphatic mapping for sentinel node biopsy by natural orifice transluminal endoscopic surgery (NOTES)
This video demonstrates fully how NOTES can facilitate 'cherry-picking' of sentinel nodes from the perigastric lymph basins (including the retropyloric space) after gastroscopic lymphatic mapping of a site in the stomach in an experimental model. It is proposed that this could be partnered with advanced endoscopic resective techniques such as Submucosal Endoscopic Dissection (SED) in order to allow definitive endoscopic excision of early stage gastric cancers.
This video is reproduced here by kind permission of Surgical Endoscopy.
2008 Sep 24. [Epub ahead of print]. PMID: 18813997 [PubMed - as supplied by publisher]